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Research groups Research groups
Translational and clinical research Translational and clinical research
Publications Publications
Annual Reports Annual Reports
European Research Council (ERC) European Research Council (ERC)
Innovation and technology projects Innovation and technology projects

Overview
Cancer Immunotherapy (Calcinotto)
Experimental Hematology (Rossi)
Experimental Therapeutics (Catapano)
Functional Cancer Genomics (Theurillat)
Lymphoma Genomics (Bertoni)
Molecular Oncology (Alimonti)
Prostate Cancer Biology (Carbone)
Stem Cells and Cancer

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Characterization of the immune landscape of human breast and ovarian tumours
A co-clinical approach to study the immune evolution of breast cancer
The contribution of tumour-infiltrating myeloid cells in dictating tumour clonal evolution
The role of the gut and tissue-associated microbiota in shaping the tumour-infiltrating immune response

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Adaptation of chronic lymphocytic leukemia to ibrutinib
Genetic and phenotypic attributes of splenic marginal zone lymphoma
Circulating tumor DNA uncovers the genetic and clinical heterogeneity of classic Hodgkin lymphoma

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Research projects
Epigenetic regulators and the potential of epigenetic therapies
Cancer stem cells and novel therapeutic approaches

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Synthetic lethality between truncal mutations in SPOP and ERG in prostate cancer
Prostate cancer transcriptome analysis reveals common path towards disease progression
Antagonistic driver genes in prostate cancer in genomic models

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Research projects
Team
Research Areas - Senescence and Senolytics
Research Areas - Cell signaling and modelling
Research Areas - Clinical trials
Research Areas - Immuno-oncology
Research Areas - Microbiota
Research Areas - Cancer metabolism

Partners
Publications
Team
Research projects
Epigenetics and progression of ERG fusion-positive prostate cancers
Role of ESE3/EHF factor in prostate cancer
Extracellular vesicles as mediators and biomarkers in prostate cancer
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Preclinical Imaging Facility Preclinical Imaging Facility
Experimental Pathology Experimental Pathology
Genomics Facility Genomics Facility
Comparative Biology Facility Comparative Biology Facility
Electron Microscopy Facility Electron Microscopy Facility
Flow Cytometry Facility Flow Cytometry Facility
Bioinformatics Core Unit Bioinformatics Core Unit
Mass Spectrometry Facility Mass Spectrometry Facility
Microscopy Facility Microscopy Facility
Histology, Seahorse, Ultracentrifuges Histology, Seahorse, Ultracentrifuges
Protein Production Facility Protein Production Facility

Education and training Education and training
PhD Program PhD Program

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Technology Transfer Office

The Technology Transfer Office at IOR, embedded within USI Transfer – Technology Transfer Office at USI, facilitates the transfer of knowledge and technologies from academia to industry, fostering innovation with practical applications. It supports researchers in finding industrial partners, evaluating the innovative potential of scientific results, and securing intellectual property protections. Additionally, it manages intellectual property provisions in commercial agreements, assesses patentability, submits patent applications, and drafts essential agreements and documents to enable effective collaboration between research and industry.