Preclinical Imaging Facility
Gianluca Civenni, PhD
The IOR Preclinical Imaging Facility (PIF) is a core facility that provides support to researchers working with preclinical small-animal models. The intent is to offer a range of technologies and equipment to perform non-invasive longitudinal imaging studies.
The PIF is integrated within the small-animal facility shared with IRB, IOR and EOC researchers. Its main objective is to develop and make available to the scientific community in Ticino non-invasive imaging technologies to visualize physiological and pathological processes in vivo in small-animal models.
The PIF supports also basic research and translational studies aimed at developing new high-end in vivo imaging approaches that might improve data quality and reproducibility, while minimizing the impact on animal wellbeing and reducing numbers of animals per individual studies.
The Facility is equipped with an in vivo luminescence and fluorescence imaging system (IVIS Spectrum) with all the accessory equipment and laboratory space for small animal studies in the spf facility. The Facility will be soon equipped with a preclinical Magnetic Resonance Imaging (MRI), and upgraded with Ultrasound (US) and Computed Tomography (CT) imaging systems.
The Facility provides support for preclinical imaging primarily to the researchers at the IOR, IRB and other Institutes in Ticino. In addition, the PIF personnel provides to all users training on animal handling, imaging and data analysis along with consulting on experimental plans