Team - Functional Cancer Genomics Lab
Group Leader: Jean-Philippe Theurillat MD
Jean-Philippe Theurillat studied Medicine at the University of Zurich, where he received his Federal Diploma in Human Medicine in 1999. Specializing first in Internal Medicine and then in Surgical Pathology at the University Hospital in Zurich and CHUV in Lausanne, he then obtained his certificate in pathology in 2007. After a period as a PostDoc at ETH and in Boston, he received funding as a boursier professor from the SNF in 2014, which allowed him to develop his research interests at the IOR. His work has been recognized by several awards, including the Pfizer Prize for Oncology Research in 2012 and the Astellas Prize in 2017. Since 2019, Prof. Theurillat is a tenured professor at the Faculty of Biomedical Sciences at USI.
He is the author of more than 30 scientific publications and his major contributions include:
- Identification of TRIM24 as a transcriptional regulator implicated in advanced castra- tion-resistant cancers.
- Identifications of recurrent mutations in the SPOP gene in prostate cancer and endometrial cancer.
- Development of a prostate cancer molecular atlas with data derived from primary and metastatic specimens (pcaprofiler.com) that will allow the discovery of molecular pathways of tumor progression and development of new therapies.
Members
Bolis Marco, Senior Investigator
Bossi Daniela, PostDoc
Bressan Silvia, PostDoc
Coazzoli Marco, Research Assistant
Corpetti Matteo, PhD Student
Costanzo Federico, Research Associate
Formaggio Nicolò, PhD Student
Gianfanti Federico, PostDoc
Impellizzieri Daniela, Research Associate
Lorenzi Claudio, Bioinformatician
Nicastri Simone, Bioinformatician
Theurillat Jean-Philippe, Group leader
Vallerga Arianna, PhD Student
Zhang Jichang, Bioinformatician
