Publications - Experimental Therapeutics Lab
Relevant publications
- Ippolito L, Duatti A, Iozzo M, Comito G, Pardella E, Lorito N, Bacci M, Pranzini E, Santi A, Sandrini G, Catapano CV, Serni S, Spatafora P, Morandi A, Giannoni E and Chiarugi P. Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer. EMBO Rep (2024) 25, 3506-3531.
https://www.ncbi.nlm.nih.gov/pubmed/38907027. - Cacciatore A, Shinde D, Musumeci C, Sandrini G, Guarrera L, Albino D, Civenni G, Storelli E, Mosole S, Federici E, Fusina A, Iozzo M, Rinaldi A, Pecoraro M, Geiger R, Bolis M, Catapano CV and Carbone GM. Epigenome-wide impact of MAT2A sustains the androgen-indifferent state and confers synthetic vulnerability in ERG fusion-positive prostate cancer. Nat Commun (2024) 15, 6672.
https://www.ncbi.nlm.nih.gov/pubmed/39107274. - Canale FP, Neumann J, von Renesse J, Loggi E, Pecoraro M, Vogel I, Zoppi G, Antonini G, Wolf T, Jin W, Zheng X, La Barba G, Birgin E, Forkel M, Nilsson T, Marone R, Mueller H, Pelletier N, Jeker LT, Civenni G, Schlapbach C, Catapano CV, Seifert L, Seifert AM, Gillessen S, De Dosso S, Cristaudi A, Rahbari NN, Ercolani G and Geiger R. Proteomics of immune cells from liver tumors reveals immunotherapy targets. Cell Genom (2023) 3, 100331.
https://www.ncbi.nlm.nih.gov/pubmed/37388918. - Sharma S, Pisignano G, Merulla J, Catapano CV and Varani G. A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript. Nucleic Acids Res(2022).
https://www.ncbi.nlm.nih.gov/pubmed/36243981. - Lekka E, Kokanovic A, Mosole S, Civenni G, Schmidli S, Laski A, Ghidini A, Iyer P, Berk C, Behera A, Catapano CV and Hall J. Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver disease. Nat Commun (2022) 13, 7940.
https://www.ncbi.nlm.nih.gov/pubmed/36572670. - Ippolito L, Comito G, Parri M, Iozzo M, Duatti A, Virgilio F, Lorito N, Bacci M, Pardella E, Sandrini G, Bianchini F, Damiano R, Ferrone L, la Marca G, Serni S, Spatafora P, Catapano CV, Morandi A, Giannoni E and Chiarugi P. Lactate Rewires Lipid Metabolism and Sustains a Metabolic-Epigenetic Axis in Prostate Cancer. Cancer Res (2022) 82, 1267-1282.
- Zoma M, Curti L, Shinde D, Albino D, Mitra A, Sgrignani J, Mapelli SN, Sandrini G, Civenni G, Merulla J, Chiorino G, Kunderfranco P, Cacciatore A, Kokanovic A, Rinaldi A, Cavalli A, Catapano CV and Carbone GM. EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer. Nat Commun (2021) 12, 4147.
https://www.ncbi.nlm.nih.gov/pubmed/34230470. - Vazquez R, Civenni G, Kokanovic A, Shinde D, Cantergiani J, Marchetti M, Zoppi G, Ruggeri B, Liu PCC, Carbone GM and Catapano CV. Efficacy of Novel Bromodomain and Extraterminal Inhibitors in Combination with Chemotherapy for Castration-Resistant Prostate Cancer. Eur Urol Oncol (2021) 4, 437-446.
https://www.ncbi.nlm.nih.gov/pubmed/31402217. - Mapelli SN, Napoli S, Pisignano G, Garcia-Escudero R, Carbone GM and Catapano CV. Deciphering the complexity of human non-coding promoter-proximal transcriptome. Bioinformatics (2019) 35, 2529-2534.
https://www.ncbi.nlm.nih.gov/pubmed/30535182. - Civenni G, Bosotti R, Timpanaro A, Vazquez R, Merulla J, Pandit S, Rossi S, Albino D, Allegrini S, Mitra A, Mapelli SN, Vierling L, Giurdanella M, Marchetti M, Paganoni A, Rinaldi A, Losa M, Mira-Cato E, D'Antuono R, Morone D, Rezai K, D'Ambrosio G, Ouafik L, Mackenzie S, Riveiro ME, Cvitkovic E, Carbone GM and Catapano CV. Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer. Cell Metab (2019) 30, 303-318 e306.
https://www.ncbi.nlm.nih.gov/pubmed/31130467.
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Institute of Oncology Research
Via Francesco Chiesa 5
6500 Bellinzona, Switzerland
tel +41 58 666 7011
e-mail info@ior.usi.ch
IOR
6500 Bellinzona, Switzerland
tel +41 58 666 7011
e-mail info@ior.usi.ch
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